About
SNRAI data scientists and software engineers develop data-driven models that leverage the surprising connection between signal sparsity and the immune status of the tumor microenvironment (TME) to better predict how a cancer patient will respond to ICB and other immunotherapies.
SNRAI is developing an internal database of immunological signatures that are likely predictors of ICB response and/or overall survival in multiple cancers based on the analysis of all cancers in The Cancer Genome Atlas using an analysis pipeline based on SSP techniques.
SNRAI is developing a cloud-based version of a SSP pipeline that runs in Jupyter notebooks to facilitate the wider use of SSP techniques in biomarker discovery and predictive modeling of cancer and other complex diseases.
Publications
Okimoto, G., Zeinalzadeh, A., Wenska, T., Loomis, M., Nation, J., Fabre, T., Tiirikainen, M., Hernandez, B., Chan, O., Wong, L. & Kwee, S. (2016)
Read MoreZeinalzadeh, A., Wenska, T. & Okimoto, G. (2016)
Read MoreOkimoto, G. (2007)
Read MoreParker, M., Mooradian, G., Okimoto, G., O’Connor, D., Miyazawa, K. & Saggese, S. (2002)
Read MoreOkimoto, G. & Lemonds, D. (1999)
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